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Place the chicken pieces in a bowl and toss with olive oil, salt, pepper, garlic powder, paprika, and onion powder.
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Coat each piece in breadcrumbs or panko, pressing lightly so the crumbs stick.
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Preheat the air fryer to 400°F (200°C). Spray the basket lightly with cooking spray.
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Arrange the chicken poppers in a single layer. Spray the tops with a little more cooking spray.
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Air fry for 8 to 10 minutes, shaking the basket halfway, until the poppers are crisp and cooked through.
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Serve warm with your favorite dip such as honey mustard, spicy mayo, or barbecue sauce.